Epithelial–Mesenchymal Transition in Chronic Rhinosinusitis: Differences Revealed Between Epithelial Cells from Nasal Polyps and Inferior Turbinates
نویسندگان
چکیده
منابع مشابه
Symptoms in chronic rhinosinusitis with and without nasal polyps.
OBJECTIVES/HYPOTHESIS In this study we analyzed differences in symptoms scored between chronic rhinosinusitis patients with (CRSwNP) and without nasal polyps (CRSsNP). According to the European Position Paper on Rhinosinusitis and Nasal Polyps, CRSwNP and CRSsNP diagnoses are defined by clinical criteria supported with endoscopy. We wanted to know if it is possible to make an accurate distincti...
متن کاملComparison of Expression of Cytokeratin 7 on Epithelium of Nasal Polyps and Mucosa of Chronic Rhinosinusitis
Background and Objective: Nasal polyp is the most common benign mass of the nasal cavity and it is originated from nasal cavity or sinuses. Cytokeratins (CK) are intermediate filament proteins that provide mechanical support in epithelial cells. The purpose of this study was to compare the expression of cytokeratin 7 in epithelium of nasal polyps and nasal mucosa in chronic rhinosinusitis. Mate...
متن کاملPrecision Medicine in Chronic Rhinosinusitis with Nasal Polyps
PURPOSE OF REVIEW Chronic rhinosinusitis is a disease with high prevalence, significant impact on health-related quality of life (HRQoL) and it is associated with substantial healthcare and productivity costs. We face an urgent need to improve the level of disease control and achieve higher patient satisfaction and disease prevention. Precision medicine is increasingly recognized as the way for...
متن کاملPeriostin as a Biomarker for Nasal Polyps in Chronic Rhinosinusitis.
Objective Periostin is an extracellular matrix protein that is elevated in the sinonasal tissues of patients with chronic rhinosinusitis (CRS). The purpose of this study was to determine whether serum periostin could serve as a molecular biomarker of nasal polyp burden in sinonasal disease. Study Design Prospective cohort study. Setting Academic medical center. Subjects and Methods Serum perios...
متن کاملSymptoms of chronic rhinosinusitis with and without nasal polyps
Background According to EPOS, chronic rhinosinusitis with and without nasal polyps diagnoses are defined by clinical criteria, supported with endoscopy. We want to know if it is possible to make an accurate distinction between patients with and without nasal polyps based on a limited number of clinical criteria, collected by health-related quality of life questionnaires. A validated instrument ...
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ژورنال
عنوان ژورنال: Archivum Immunologiae et Therapiae Experimentalis
سال: 2016
ISSN: 0004-069X,1661-4917
DOI: 10.1007/s00005-016-0409-7